MT 2 10MG

🔬 Product Code: MT2-10MG

🧪 Specification: 10mg Lyophilized Powder

🧬 Purity: ≥99% Verified via HPLC / MS

⚠️ Application: For In-Vitro and Preclinical Laboratory Research Only. Not for human or veterinary use.

Product Overview

Melanotan II (MT-2) is a synthetic analog of the naturally occurring peptide hormone $\alpha$-Melanocyte-Stimulating Hormone ($\alpha$-MSH). Structurally, it is a cyclic heptapeptide with the amino acid sequence Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2, engineered to possess a significantly higher stability profile and extended half-life compared to its endogenous counterpart.

In biochemical and dermatological research, Melanotan II functions as a potent, non-selective agonist of systemic melanocortin receptors (MCRs), demonstrating high affinity for the MC1, MC3, MC4, and MC5 receptor subtypes:

• MC1R Activation: Located on cutaneous melanocytes. Stimulation of this pathway accelerates melanogenesis—the cellular process responsible for the synthesis and proliferation of eumelanin (dark brown/black pigment) in skin tissue models.

• MC4R Activation: Positioned centrally within the hypothalamus. Agonism at this receptor is studied for its downstream effects on energy homeostasis, appetite suppression, and the regulation of erectile function and sexual behavior in animal models.

Key Research Applications

• Melanogenesis & Photoprotection Modeling: Investigating the cellular signaling cascades that trigger pigmentation updates independent of harmful ultraviolet (UV) radiation exposure.

• Appetite and Metabolic Regulation: Mapping hypothalamic MC4R pathways to analyze changes in calorie consumption and energy expenditure in metabolic tissue assays.

• Neurogenic Erectile Function Studies: Evaluating central nervous system mechanisms and vascular responses governing erectile signaling in physiological models.

Uncompromising Quality Control

Every batch of Melanotan II distributed by Onyx Research undergoes independent, third-party analytical testing to guarantee reproducible experimental results.

• High-Performance Liquid Chromatography (HPLC): Confirms an exact purity profile exceeding 99%.

• Mass Spectrometry (MS): Verifies correct sequence identity, cyclic structure, and precise molecular weight ($1024.2\text{ Da}$).

• Lyophilization Technology: Vacuum-sealed to ensure optimal structural stability during transport and storage.

Handling & Storage Guidelines

• Form: Lyophilized (freeze-dried) white crystalline powder.

• Reconstitution: For laboratory testing, reconstitute using sterile bacteriostatic water. Guide the fluid gently down the internal glass wall of the vial and swirl slowly. Do not shake or agitate aggressively to prevent peptide shear.

• Storage (Lyophilized): Stable at room temperature for up to 4 weeks during transit. Store long-term at $-20^\circ\text{C}$ to preserve peptide integrity for up to 24 months.

• Storage (Reconstituted): Once in solution, store under refrigeration at $2^\circ\text{C}$ to $8^\circ\text{C}$ and utilize within 10 to 14 days for optimal experimental consistency.

Laboratory Safety Disclaimer: This compound is supplied exclusively to qualified professionals, academic institutions, and commercial laboratories engaged in scientific innovation. Onyx Research explicitly prohibits the administration of this material to humans or animals. All handling must conform to strict laboratory safety standards, including the use of proper personal protective equipment (PPE).