GLP2-TZ 10MG

🔬 Product Code: GLP2-TZ-10MG

🧪 Specification: 10mg Lyophilized Powder

🧬 Purity: ≥99% Verified via HPLC / MS

⚠️ Application: For In-Vitro and Preclinical Laboratory Research Only. Not for human or veterinary use.

Product Overview

GLP2-TZ (scientifically known as Tirzepatide, research code LY3298176) is a landmark synthetic peptide engineered as a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist. Structurally, it consists of a single 39-amino acid chain containing a C20 fatty diacid section that dynamically extends its experimental half-life to approximately 5 days via albumin binding.

Often referred to as a “twincretin” in metabolic literature, GLP2-TZ is globally studied for its distinct, dual-pathway mechanism of action. Rather than targeting the GLP-1 receptor in isolation, this molecule activates both key metabolic pathways to maximize pancreatic beta-cell response, delay gastric transit, and modify neurological satiety signals. In preclinical animal assays, this combined agonism demonstrates a highly profound impact on energy balance and glycemic control compared to older single-agonist solutions.

Key Research Applications

• Dual Incretin Pathway Synergy: Mapping out the physiological crosstalk and enhanced cellular signaling achieved by simultaneously stimulating GIP and GLP-1 receptors.

• Glycemic Control & Insulin Secretion: Investigating nutrient-dependent insulin release and glucagon suppression dynamics within experimental tissue models.

• Adiposity and Satiety Regulation: Analyzing long-term adjustments in calorie consumption, energy expenditure, and fat tissue distribution under sustained receptor saturation.

Uncompromising Quality Control

Every batch of GLP2-TZ distributed by Onyx Research undergoes rigorous, independent analytical validation to safeguard the accuracy of your scientific trials.

• High-Performance Liquid Chromatography (HPLC): Confirms an exact baseline purity profile exceeding 99%.

• Mass Spectrometry (MS): Verifies absolute molecular identity and correct sequence composition ($4813.5\text{ Da}$).

• Lyophilization Technology: Vacuum-sealed in clinical-grade glass vials to guarantee optimal structural stability across transit and storage environments.

Handling & Storage Guidelines

• Form: Lyophilized (freeze-dried) white crystalline powder.

• Reconstitution: Reconstitute using sterile bacteriostatic water. Introduce the liquid gently down the internal glass wall of the vial and swirl slowly. Do not shake or agitate aggressively to prevent protein shearing.

• Storage (Lyophilized): Stable at room temperature for up to 4 weeks during transit. Store long-term at −20∘C to preserve peptide integrity for up to 24 months.

• Storage (Reconstituted): Once in solution, store under refrigeration at 2∘C to 8∘C and utilize within 10 to 14 days for optimal experimental consistency.

Laboratory Safety Disclaimer: This compound is supplied exclusively to qualified professionals, academic institutions, and commercial laboratories engaged in scientific innovation. Onyx Research explicitly prohibits the administration of this material to humans or animals. All handling must conform to strict laboratory safety standards, including the use of proper personal protective equipment (PPE).