Epithalon 10mg

🔬 Product Code: EPI-10MG

🧪 Specification: 10mg Lyophilized Powder

🧬 Purity: ≥99% Verified via HPLC / MS

⚠️ Application: For In-Vitro and Preclinical Laboratory Research Only. Not for human or veterinary use.

Product Overview

Epithalon (also known as Epitalon or Epithalone) is a synthetic tetrapeptide consisting of four amino acids with the sequence Ala-Glu-Asp-Gly. It is a synthetic mimic of epithalamin, a peptide bioregulator naturally produced by the pineal gland.

In molecular biology and anti-aging research, Epithalon is globally studied for its unique ability to upregulate the expression of the telomerase enzyme ($\text{TERT}$). In cellular and animal models, this upregulation facilitates the elongation of telomeres—the protective caps at the ends of chromosomes that naturally shorten as cells divide. By promoting telomere maintenance and restoring cellular proliferation caps, Epithalon serves as a vital tool for exploring the mechanisms of cellular senescence (cellular aging) and lifespand expansion pathways.

Key Research Applications

• Telomerase Activation Studies: Investigating the precise epigenetic mechanisms by which the Ala-Glu-Asp-Gly sequence binds to DNA to reactivate telomerase expression.

• Pineal Gland & Circadian Regulation: Analyzing the peptide’s capacity to restore normal melatonin synthesis and normalize sleep-wake cycles in aged animal subjects.

• Oncology & Free Radical Research: Evaluating its secondary effects on reducing oxidative stress, modulating lipid peroxidation, and influencing tumor suppression pathways in preclinical test models.

Uncompromising Quality Control

Every batch of Epithalon distributed by Onyx Research undergoes independent, third-party analytical verification to guarantee absolute data integrity.

• High-Performance Liquid Chromatography (HPLC): Confirms an exact purity profile exceeding 99%.

• Mass Spectrometry (MS): Verifies correct sequence identity and precise molecular weight ($390.3\text{ Da}$).

• Lyophilization Technology: Vacuum-sealed to ensure optimal structural stability during transport and storage.

Handling & Storage Guidelines

• Form: Lyophilized (freeze-dried) white crystalline powder.

• Reconstitution: For laboratory testing, reconstitute using sterile bacteriostatic water. Guide the fluid gently down the glass wall of the vial and swirl slowly; do not shake or agitate aggressively.

• Storage (Lyophilized): Stable at room temperature for up to 4 weeks during transit. Store long-term at $-20^\circ\text{C}$ to preserve peptide integrity for up to 24 months.

• Storage (Reconstituted): Once in solution, store under refrigeration at $2^\circ\text{C}$ to $8^\circ\text{C}$ and utilize within 10 to 14 days for optimal experimental consistency.

Laboratory Safety Disclaimer: This compound is supplied exclusively to qualified professionals, academic institutions, and commercial laboratories engaged in scientific innovation. Onyx Research explicitly prohibits the administration of this material to humans or animals. All handling must conform to strict laboratory safety standards, including the use of proper personal protective equipment (PPE).